KCNJ3
KCNJ3，全稱為鉀通道亞家族J成員3，常用別名是GIRK1。這種蛋白廣泛分布在大腦神經元、心肌細胞等組織中，常與其他亞基協同組成功能性通道，調控鉀離子的跨膜流動，以此維持細胞正常的電生理狀態。在神經系統里，KCNJ3參與調節神經信號的傳遞效率，影響神經元的興奮程度；在心臟部位，它對維持心肌節律穩定起著關鍵作用。若該蛋白功能異常，可能與癲癇等神經系統疾病的發生有關，也可能增加心房顫動等心律失常的風險。目前，針對該蛋白相關通道的藥物研發正在推進，一些候選化合物已進入臨床前研究階段，有望為相關疾病的治療提供新方向。
熱銷產品
驗證數據
-SDS.jpg)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
KCNJ3 Antibody (CSB-PA012056LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA012056LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA012056LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
KCNJ3 Antibodies
KCNJ3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA010514 | Phospho-KCNJ3 (S185) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA010515 | KCNJ3 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA012056LA01HU | KCNJ3 Antibody | Human | ELISA, IHC, IF |
| CSB-PA012056LB01HU | KCNJ3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA012056LC01HU | KCNJ3 Antibody, FITC conjugated | Human | |
| CSB-PA012056LD01HU | KCNJ3 Antibody, Biotin conjugated | Human | ELISA |
KCNJ3 Proteins
KCNJ3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP012056HU1 CSB-EP012056HU1 CSB-BP012056HU1 CSB-MP012056HU1 CSB-EP012056HU1-B |
Recombinant Human G protein-activated inward rectifier potassium channel 1 (KCNJ3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012056HU | Recombinant Human G protein-activated inward rectifier potassium channel 1 (KCNJ3) | in vitro E.coli expression system |
| CSB-CF012056HU(M) | Recombinant Human G protein-activated inward rectifier potassium channel 1 (KCNJ3)(F137S) | in vitro E.coli expression system |
| CSB-MP012056HU(M) | Recombinant Human G protein-activated inward rectifier potassium channel 1 (KCNJ3) (F137S)-VLPs | Mammalian cell |
KCNJ3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP012056MO1 CSB-EP012056MO1 CSB-BP012056MO1 CSB-MP012056MO1 CSB-EP012056MO1-B |
Recombinant Mouse G protein-activated inward rectifier potassium channel 1 (Kcnj3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012056MO | Recombinant Mouse G protein-activated inward rectifier potassium channel 1 (Kcnj3) | in vitro E.coli expression system |
KCNJ3 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP012056RA1 CSB-EP012056RA1 CSB-BP012056RA1 CSB-MP012056RA1 CSB-EP012056RA1-B |
Recombinant Rat G protein-activated inward rectifier potassium channel 1 (Kcnj3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012056RA | Recombinant Rat G protein-activated inward rectifier potassium channel 1 (Kcnj3) | in vitro E.coli expression system |
KCNJ3 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP820881CH1 CSB-EP820881CH1 CSB-BP820881CH1 CSB-MP820881CH1 CSB-EP820881CH1-B |
Recombinant Chicken G protein-activated inward rectifier potassium channel 1 (KCNJ3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF820881CH | Recombinant Chicken G protein-activated inward rectifier potassium channel 1 (KCNJ3) | in vitro E.coli expression system |
