KRT35
KRT35，全稱為角蛋白35，也常被稱為毛發(fā)角蛋白35，是角蛋白家族中具有毛發(fā)特異性的成員。它主要存在于毛發(fā)的皮質(zhì)層細胞里，作為構(gòu)成毛發(fā)纖維的核心成分之一，為毛發(fā)提供必要的強度和彈性，讓毛發(fā)能抵抗日常摩擦，保持順滑堅韌的狀態(tài)。
當KRT35表達水平異常或結(jié)構(gòu)改變時，可能導(dǎo)致毛發(fā)結(jié)構(gòu)出現(xiàn)缺陷，比如毛發(fā)變脆易斷、卷曲形態(tài)異常（如羊毛狀發(fā)），甚至和某些類型的脫發(fā)相關(guān)。目前針對它的藥物研發(fā)還處于早期階段，研究人員主要在解析它在毛發(fā)疾病中的具體角色，同時嘗試開發(fā)能調(diào)節(jié)其功能的干預(yù)手段，比如一些改善毛發(fā)健康的外用制劑或靶向療法正在初步實驗室研究中，有望為毛發(fā)相關(guān)疾病的治療提供新方向。
熱銷產(chǎn)品
Recombinant Human Keratin, type I cuticular Ha5 (KRT35) (CSB-EP856422HUa0)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
KRT35 Antibody (CSB-PA856422LA01HU)
驗證數(shù)據(jù)
Western blot
All lanes: KRT35 antibody at 4µg/ml + PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA856422LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA856422LA01HU at dilution of 1:100
KRT35 Antibodies
KRT35 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA856422LA01HU | KRT35 Antibody | Human | ELISA, WB, IHC |
| CSB-PA856422LB01HU | KRT35 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA856422LC01HU | KRT35 Antibody, FITC conjugated | Human | |
| CSB-PA856422LD01HU | KRT35 Antibody, Biotin conjugated | Human | ELISA |
KRT35 Proteins
KRT35 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012551SH CSB-EP012551SH CSB-BP012551SH CSB-MP012551SH CSB-EP012551SH-B |
Recombinant Sheep Keratin, type I cuticular Ha5 (KRT35) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KRT35 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP612675BO CSB-EP612675BO CSB-BP612675BO CSB-MP612675BO CSB-EP612675BO-B |
Recombinant Bovine Keratin, type I cuticular Ha5 (KRT35) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KRT35 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP676581MO CSB-EP676581MO CSB-BP676581MO CSB-MP676581MO CSB-EP676581MO-B |
Recombinant Mouse Keratin, type I cuticular Ha5 (Krt35) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KRT35 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP856422HU | Recombinant Human KeRatin, type I cuticular Ha5 (KRT35) | Yeast |
| CSB-EP856422HU | Recombinant Human Keratin, type I cuticular Ha5 (KRT35) | E.coli |
| CSB-BP856422HU CSB-MP856422HU CSB-EP856422HU-B |
Recombinant Human KeRatin, type I cuticular Ha5 (KRT35) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP856422HUa0 | Recombinant Human Keratin, type I cuticular Ha5 (KRT35) | E.coli |
