LTA
LTA，全稱為脂磷壁酸，常見(jiàn)別名有膜磷壁酸、LTA脂壁酸，是革蘭氏陽(yáng)性菌細(xì)胞壁的重要組成成分，屬于兩親性分子。它廣泛存在于乳酸桿菌、金黃色葡萄球菌等細(xì)菌表面，可通過(guò)自身結(jié)構(gòu)介導(dǎo)細(xì)菌與宿主上皮細(xì)胞的黏附定植，同時(shí)參與機(jī)體免疫調(diào)節(jié)，平衡炎癥因子釋放，維持腸道菌群與免疫穩(wěn)態(tài)，還能維持細(xì)菌自身細(xì)胞形態(tài)與離子平衡。
LTA異常表達(dá)或結(jié)構(gòu)異常與多種疾病相關(guān)，既涉及強(qiáng)直性脊柱炎、系統(tǒng)性紅斑狼瘡等自身免疫性疾病，也與肝癌、食管癌等惡性腫瘤密切相關(guān)，同時(shí)是“超級(jí)細(xì)菌”致病性的關(guān)鍵分子。目前相關(guān)研發(fā)聚焦于抗菌與抗腫瘤領(lǐng)域，針對(duì)其結(jié)構(gòu)修飾的新型抗生素正處于臨床前研究，部分靶向抑制劑可協(xié)同免疫治療提升腫瘤療效，為相關(guān)疾病治療提供了新方向。
熱銷產(chǎn)品
Recombinant Human Lymphotoxin-alpha (LTA) (Active) (CSB-MP013218HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized LTA at 5 μg/ml can bind human TNFRSF1B (CSB-MP023978HU2), the EC50 is 1.632-2.699 ng/ml.
Activity
Measured by its binding ability in a functional ELISA. Immobilized LTA at 5 μg/ml can bind human TNFR1(CSB-MP023977HU1), the EC50 of human LTA protein is 4.409-6.797 ng/ml.
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA863040(LTA Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA863040(LTA Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
Human Tumor necrosis factor β,TNF-β ELISA KIT (CSB-E04743h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E04743h
規(guī)格：96T/48T
靈敏度：3.9 pg/mL
檢測(cè)范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
LTA Antibodies
LTA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA013218KA01HU | LTA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA004313 | LTA Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA863040 | LTA Antibody | Human | ELISA,IHC |
| CSB-RA013218A0HU | LTA Recombinant Monoclonal Antibody | Human | ELISA |
LTA Proteins
LTA Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013218RB CSB-EP013218RB CSB-BP013218RB CSB-MP013218RB CSB-EP013218RB-B |
Recombinant Rabbit Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013218PI CSB-EP013218PI CSB-BP013218PI CSB-MP013218PI CSB-EP013218PI-B |
Recombinant Pig Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013218HU CSB-EP013218HU CSB-BP013218HU CSB-EP013218HU-B |
Recombinant Human Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP002171HU | Recombinant Human Lymphotoxin-alpha protein (LTA) | E.Coli |
| CSB-AP004941HU | Recombinant Human Lymphotoxin-alpha (LTA) (Active) | E.coli |
| CSB-MP013218HU | Recombinant Human Lymphotoxin-alpha (LTA) (Active) | Mammalian cell |
| CSB-MP013218HU-B | Recombinant Human Lymphotoxin-alpha (LTA), partial,Biotinylated | Mammalian cell |
LTA Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013218MO CSB-BP013218MO CSB-MP013218MO CSB-EP013218MO-B |
Recombinant Mouse Lymphotoxin-alpha (Lta) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP013218MO | Recombinant Mouse Lymphotoxin-alpha (Lta) | E.coli |
| CSB-EP013218MOa0 | Recombinant Mouse Lymphotoxin-alpha (Lta) | E.coli |
LTA Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013218EQV CSB-EP013218EQV CSB-BP013218EQV CSB-MP013218EQV CSB-EP013218EQV-B |
Recombinant Pan troglodytes Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP713142MOW CSB-EP713142MOW CSB-BP713142MOW CSB-MP713142MOW CSB-EP713142MOW-B |
Recombinant Macaca mulatta Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP730213DO CSB-EP730213DO CSB-BP730213DO CSB-MP730213DO CSB-EP730213DO-B |
Recombinant Dog Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA Proteins for Marmota monax (Woodchuck)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP862417MQG CSB-EP862417MQG CSB-BP862417MQG CSB-MP862417MQG CSB-EP862417MQG-B |
Recombinant Marmota monax Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA Proteins for Macropus eugenii (Tammar wallaby)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP894074MPE CSB-EP894074MPE CSB-BP894074MPE CSB-MP894074MPE CSB-EP894074MPE-B |
Recombinant Macropus eugenii Lymphotoxin-alpha (LTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LTA ELISA Kit
LTA ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04743h | Human Tumor necrosis factor β,TNF-β ELISA KIT | serum, plasma, cell culture supernates | 3.9 pg/mL |
LTA ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04744m | Mouse Tumor necrosis factor β,TNF-β ELISA KIT | serum, plasma, tissue homogenates | 4.7 pg/mL |
LTA ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07379r | Rat Tumor necrosis factor β,TNF-β ELISA KIT | serum, plasma, tissue homogenates | 1.95 pg/mL |
