MAPK3
MAPK3，全稱(chēng)為絲裂原活化蛋白激酶3，常見(jiàn)別名包括ERK1。它是細(xì)胞內(nèi)關(guān)鍵的信號(hào)傳遞分子，參與調(diào)控細(xì)胞生長(zhǎng)、增殖、分化及凋亡等多種生命過(guò)程。當(dāng)細(xì)胞受到生長(zhǎng)因子、激素或外界環(huán)境刺激時(shí)，它會(huì)被激活并啟動(dòng)下游一系列分子反應(yīng)，幫助細(xì)胞做出相應(yīng)的生理調(diào)整。
在疾病領(lǐng)域，MAPK3活性異常常與癌癥密切相關(guān)，比如非小細(xì)胞肺癌、乳腺癌、結(jié)直腸癌等。一旦它過(guò)度活躍，可能導(dǎo)致細(xì)胞增殖失控，推動(dòng)腫瘤的發(fā)生、侵襲和轉(zhuǎn)移。目前針對(duì)這一蛋白的藥物研發(fā)正在推進(jìn)，一些小分子抑制劑已進(jìn)入臨床試驗(yàn)階段，這類(lèi)藥物希望通過(guò)調(diào)節(jié)它的活性來(lái)抑制腫瘤細(xì)胞生長(zhǎng)，為相關(guān)癌癥治療提供新方向。
熱銷(xiāo)產(chǎn)品
MAPKAPK3 Antibody (CSB-PA620974ESR1HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: MAPKAPK3 antibody at 4.4µg/ml
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 43 kDa
Observed band size: 43 kDa
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA620974ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA620974ESR1HU at dilution of 1:100
MAPK3 Antibodies
MAPK3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA013456GA01HU | MAPK3 Antibody | Human,Mouse,Rat,Zebrafish | ELISA,WB,IHC |
| CSB-PA013456LA01HU | MAPK3 Antibody | Human, Mouse, Rat | ELISA, WB, IHC, IF |
| CSB-PA245959 | Phospho-MAPK3 (Thr202) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA089297 | Phospho-MAPK3 (Tyr204) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA955942 | MAPK3 (Ab-202) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA070105 | MAPK3 (Ab-204) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA272447 | MAPK3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA931769 | MAPK3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA247267 | MAPKAPK3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA000766 | MAPKAPK3 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA002417 | MAPK3 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA037845 | MAPK3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA620974ESR1HU | MAPKAPK3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA321775 | MAPK3 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-RA013456A185phHU | Phospho-MAPK3 (T202) + MAPK1 (T185) Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF |
MAPK3 Proteins
MAPK3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP013456RA CSB-EP013456RA CSB-BP013456RA CSB-MP013456RA CSB-EP013456RA-B |
Recombinant Rat Mitogen-activated protein kinase 3 (Mapk3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-BP013456HU CSB-MP013456HU CSB-EP013456HU(A5)-B |
Recombinant Human Mitogen-activated protein kinase 3 (MAPK3) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP620974HU CSB-EP620974HU CSB-BP620974HU CSB-MP620974HU CSB-EP620974HU-B |
Recombinant Human MAP kinase-activated protein kinase 3 (MAPKAPK3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP013456HU | Recombinant Human Mitogen-activated protein kinase 3 (MAPK3), partial | E.coli |
| CSB-EP013456HU(A5) | Recombinant Human Mitogen-activated protein kinase 3 (MAPK3) | E.coli |
| CSB-YP013456HU(A5) | Recombinant Human Mitogen-activated protein kinase 3 (MAPK3) | Yeast |
MAPK3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP013456MO CSB-EP013456MO CSB-BP013456MO CSB-MP013456MO CSB-EP013456MO-B |
Recombinant Mouse Mitogen-activated protein kinase 3 (Mapk3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
