MAVS
MAVS，全稱為線粒體抗病毒信號蛋白，常用別名IPS-1、VISA。它定位于線粒體，是固有免疫應答中的關鍵信號蛋白，能夠識別病毒感染信號，啟動抗病毒免疫反應，促進干擾素及抗炎細胞因子分泌，清除入侵病毒，維持機體抗病毒防御穩態。 MAVS功能異常與病毒感染、自身免疫病及腫瘤密切相關，功能缺陷會降低機體抗病毒能力，易引發嚴重病毒感染；異常活化則誘發慢性炎癥與自身免疫疾病，同時也參與腫瘤免疫微環境調控。目前MAVS激動劑與抑制劑處于臨床前研究階段，通過調控免疫應答，為病毒感染、自身免疫病及腫瘤提供新型干預方向。
熱銷產品
Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial (CSB-EP772018HUc0)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA179571(MAVS Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA179571(MAVS Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
MAVS Antibodies
MAVS for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013526GA01HU | MAVS Antibody | Human | ELISA,WB,IF |
| CSB-PA772018ESR2HU | MAVS Antibody | Human | ELISA |
| CSB-PA179571 | MAVS Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA846893 | MAVS Antibody | Human,Mouse | ELISA,WB,IHC |
MAVS Proteins
MAVS Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP721076RA CSB-EP721076RA CSB-BP721076RA CSB-MP721076RA CSB-EP721076RA-B |
Recombinant Rat Mitochondrial antiviral-signaling protein (Mavs), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAVS Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP772018HU CSB-EP772018HU CSB-BP772018HU CSB-MP772018HU |
Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial | Yeast E.coli Baculovirus Mammalian cell |
| CSB-EP772018HUa2 | Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial | E.coli |
| CSB-EP772018HUc0 | Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial | E.coli |
| CSB-EP772018HU-B | Recombinant Human Mitochondrial antiviral-signaling protein (MAVS), partial,Biotinylated | E.coli |
MAVS Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP844990MO CSB-EP844990MO CSB-BP844990MO CSB-MP844990MO CSB-EP844990MO-B |
Recombinant Mouse Mitochondrial antiviral-signaling protein (Mavs), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
