MC5R
黑素皮質素受體5（MC5R）是G蛋白偶聯受體家族的一員，常見別名包括MC5-R。它廣泛分布在腎上腺、脂肪組織、免疫細胞等部位，參與調控身體多項生理過程。在脂肪組織中，它能影響脂肪的分解與儲存，與身體能量平衡的維持緊密相關；在免疫細胞中，它可能參與炎癥反應的調節，幫助維持免疫穩態。
若MC5R功能出現異常，可能導致代謝紊亂，如肥胖、脂質代謝異常等問題，也可能與某些炎癥性疾病的發生發展有關。目前，針對MC5R的靶向藥物研究正在推進，科研人員試圖通過調節其活性來改善代謝綜合征或炎癥相關病癥，部分候選藥物已進入早期臨床試驗階段，但尚未有成熟藥物應用于臨床。
熱銷產品
Recombinant Human Melanocortin receptor 5 (MC5R) (CSB-CF013562HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MC5R Antibody (CSB-PA013562LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013562LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA013562LA01HU at dilution of 1:100
Immunofluorescence staining of MCF-7 cells with CSB-PA013562LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
MC5R Antibodies
MC5R for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA003205 | MC5R Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA067089 | MC5R Antibody | Human | ELISA,IHC |
| CSB-PA091719 | MC5R Antibody | Human,Mouse | ELISA,WB |
| CSB-PA013562LA01HU | MC5R Antibody | Human | ELISA, IHC, IF |
| CSB-PA013562LB01HU | MC5R Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013562LC01HU | MC5R Antibody, FITC conjugated | Human | |
| CSB-PA013562LD01HU | MC5R Antibody, Biotin conjugated | Human | ELISA |
MC5R Proteins
MC5R Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013562RA1 CSB-EP013562RA1 CSB-BP013562RA1 CSB-MP013562RA1 CSB-EP013562RA1-B |
Recombinant Rat Melanocortin receptor 5 (Mc5r), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF013562RA | Recombinant Rat Melanocortin receptor 5 (Mc5r) | in vitro E.coli expression system |
MC5R Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013562MO1 CSB-EP013562MO1 CSB-BP013562MO1 CSB-MP013562MO1 CSB-EP013562MO1-B |
Recombinant Mouse Melanocortin receptor 5 (Mc5r), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF013562MO | Recombinant Mouse Melanocortin receptor 5 (Mc5r) | in vitro E.coli expression system |
MC5R Proteins for Ovis aries (Sheep)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013562SH1 CSB-EP013562SH1 CSB-BP013562SH1 CSB-MP013562SH1 CSB-EP013562SH1-B |
Recombinant Sheep Melanocortin receptor 5 (MC5R), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF013562SH | Recombinant Sheep Melanocortin receptor 5 (MC5R) | in vitro E.coli expression system |
MC5R Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013562HU1 CSB-EP013562HU1 CSB-BP013562HU1 CSB-MP013562HU1 CSB-EP013562HU1-B |
Recombinant Human Melanocortin receptor 5 (MC5R), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF013562HU | Recombinant Human Melanocortin receptor 5 (MC5R) | in vitro E.coli expression system |
MC5R Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013562BO1 CSB-EP013562BO1 CSB-BP013562BO1 CSB-MP013562BO1 CSB-EP013562BO1-B |
Recombinant Bovine Melanocortin receptor 5 (MC5R), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF013562BO | Recombinant Bovine Melanocortin receptor 5 (MC5R) | in vitro E.coli expression system |
MC5R Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP863073PI1 CSB-EP863073PI1 CSB-BP863073PI1 CSB-MP863073PI1 CSB-EP863073PI1-B |
Recombinant Pig Melanocortin receptor 5 (MC5R), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF863073PI | Recombinant Pig Melanocortin receptor 5 (MC5R) | in vitro E.coli expression system |
MC5R Proteins for Pan troglodytes (Chimpanzee)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP866132EQV1 CSB-EP866132EQV1 CSB-BP866132EQV1 CSB-MP866132EQV1 CSB-EP866132EQV1-B |
Recombinant Pan troglodytes Melanocortin receptor 5 (MC5R), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF866132EQV | Recombinant Pan troglodytes Melanocortin receptor 5 (MC5R) | in vitro E.coli expression system |
