MLC1
MLC1，全稱為巨腦性白質腦病伴皮質下囊腫蛋白1，常用別名有VRAC電流調節蛋白1、LVM。它是主要表達在大腦星形膠質細胞上的膜蛋白，參與腦組織離子與水分平衡、細胞體積穩定，對維持神經膠質正常結構與腦內環境穩態有重要作用。
MLC1功能異常是導致巨腦性白質腦病伴皮質下囊腫的主要原因，約七成以上病例與之相關，患兒常出現大頭畸形、運動障礙、癲癇發作與認知衰退。目前針對這一罕見神經遺傳病的治療仍以對癥干預為主，靶向MLC1功能修復的小分子調節劑與基因療法正處于臨床前研究階段，有望為這類疾病帶來新的治療可能。
熱銷產品
Recombinant Human Membrane protein MLC1 (MLC1)-VLPs (CSB-MP613581HU(A5))
驗證數據
-WB.jpg)
CSB-MP613581HU(A5) is detected by Mouse anti-6*His monoclonal antibody.
-HPLC.jpg)
The purity of VLPs was greater than 95% as determined by SEC-HPLC
MLC1 Antibody (CSB-PA613581LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA613581LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA613581LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
MLC1 Antibodies
MLC1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA014619GA01HU | MLC1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA613581LA01HU | MLC1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA613581LB01HU | MLC1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA613581LC01HU | MLC1 Antibody, FITC conjugated | Human | |
| CSB-PA613581LD01HU | MLC1 Antibody, Biotin conjugated | Human | ELISA |
MLC1 Proteins
MLC1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP346051SVG CSB-EP346051SVG CSB-BP346051SVG CSB-MP346051SVG CSB-EP346051SVG-B |
Recombinant Saccharomyces cerevisiae Myosin light chain 1 (MLC1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila melanogaster (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP361933DLU CSB-EP361933DLU CSB-BP361933DLU CSB-MP361933DLU CSB-EP361933DLU-B |
Recombinant Drosophila melanogaster Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila subobscura (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP528590DML CSB-EP528590DML CSB-BP528590DML CSB-MP528590DML CSB-EP528590DML-B |
Recombinant Drosophila subobscura Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP613581HU CSB-EP613581HU CSB-BP613581HU CSB-MP613581HU CSB-EP613581HU-B |
Recombinant Human Membrane protein MLC1 (MLC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP613581HU(A5) | Recombinant Human Membrane protein MLC1 (MLC1)-VLPs | Mammalian cell |
MLC1 Proteins for Drosophila sechellia (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP632806DMG CSB-EP632806DMG CSB-BP632806DMG CSB-MP632806DMG CSB-EP632806DMG-B |
Recombinant Drosophila sechellia Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila teissieri (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP634515DMO CSB-EP634515DMO CSB-BP634515DMO CSB-MP634515DMO CSB-EP634515DMO-B |
Recombinant Drosophila teissieri Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila yakuba (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP634518DMR CSB-EP634518DMR CSB-BP634518DMR CSB-MP634518DMR CSB-EP634518DMR-B |
Recombinant Drosophila yakuba Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila mauritiana (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP635524DLT CSB-EP635524DLT CSB-BP635524DLT CSB-MP635524DLT CSB-EP635524DLT-B |
Recombinant Drosophila mauritiana Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila simulans (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP635531DMJ CSB-EP635531DMJ CSB-BP635531DMJ CSB-MP635531DMJ CSB-EP635531DMJ-B |
Recombinant Drosophila simulans Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila virilis (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP636563DMP CSB-EP636563DMP CSB-BP636563DMP CSB-MP636563DMP CSB-EP636563DMP-B |
Recombinant Drosophila virilis Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP638768DME CSB-EP638768DME CSB-BP638768DME CSB-MP638768DME CSB-EP638768DME-B |
Recombinant Drosophila pseudoobscura pseudoobscura Myosin light chain alkali (Mlc1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP717178MOV CSB-EP717178MOV CSB-BP717178MOV CSB-MP717178MOV CSB-EP717178MOV-B |
Recombinant Macaca fascicularis Membrane protein MLC1 (MLC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLC1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP837739MO CSB-EP837739MO CSB-BP837739MO CSB-MP837739MO CSB-EP837739MO-B |
Recombinant Mouse Membrane protein MLC1 (Mlc1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
