MUC4
MUC4，即粘蛋白4，常見別名包括MUC-4，是一種分布在細胞表面的糖蛋白，其分子上附著大量糖鏈結(jié)構(gòu)。它能與周圍細胞或分子發(fā)生相互作用，既幫助維持細胞結(jié)構(gòu)的穩(wěn)定性，也會影響細胞的生長和移動過程。
在疾病方面，MUC4的異常表達與多種癌癥密切相關(guān)。例如胰腺癌患者體內(nèi)該蛋白水平常明顯升高，可能推動腫瘤細胞的侵襲和擴散；肺癌、胃癌等疾病中也能觀察到它的表達變化。目前針對MUC4的藥物研發(fā)正逐步推進，主要方向是開發(fā)靶向抗體來抑制其異常功能，部分候選藥物已進入早期臨床研究階段，有望為相關(guān)癌癥的治療帶來新的突破。
熱銷產(chǎn)品
MUC4 Recombinant Monoclonal Antibody (CSB-RA086101A0HU)
驗證數(shù)據(jù)
Flow cytometric analysis of MUC4 expression in HeLa cells using MUC4 antibody. Green, isotype control; red, MUC4.
Western blotting analysis using MUC4 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with MUC4 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
Human Mucin-4(MUC4) ELISA kit (CSB-EL015227HU)
驗證數(shù)據(jù)
貨號：CSB-EL015227HU
規(guī)格：96T/48T
靈敏度：0.156 ng/mL
檢測范圍：0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
MUC4 Antibodies
MUC4 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-RA086101A0HU | MUC4 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, FC |
MUC4 Proteins
MUC4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP858489HU CSB-EP858489HU CSB-BP858489HU CSB-MP858489HU CSB-EP858489HU-B |
Recombinant Human Mucin-4 (MUC4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MUC4 ELISA Kit
MUC4 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL015227HU | Human Mucin-4(MUC4) ELISA kit | serum, plasma, tissue homogenates | 0.156 ng/mL |
