NKX3-2
NKX3-2，全稱為NK3同源框2蛋白，常用別名包括BAPX1。它在人體發育中扮演著關鍵角色，尤其與骨骼和軟骨組織的形成、維持密切相關。這種蛋白能引導軟骨細胞的分化與成熟，助力關節、脊柱等部位的正常發育；若其功能出現異常，可能干擾軟骨的健康狀態，進而引發相關疾病。
臨床觀察發現，NKX3-2的表達變化與脊柱側凸、骨關節炎等骨骼疾病存在聯系。例如，部分骨關節炎患者體內該蛋白水平降低，可能加速軟骨退化；而脊柱側凸患者中也存在該蛋白的表達異常，影響骨骼發育的對稱性。目前，針對NKX3-2的研究聚焦于軟骨修復領域，科學家們嘗試通過調節其活性來促進受損軟骨再生，一些靶向該蛋白的候選分子正處于早期研發階段，有望為相關疾病提供新的治療思路。
熱銷產品
Recombinant Human Homeobox protein Nkx-3.2 (Nkx3-2) (CSB-EP015849HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NKX3-2 Antibody (CSB-PA015849LA01HU)
驗證數據
Western Blot
Positive WB detected in: Rat brain tissue
All lanes: NKX3-2 antibody at 4.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa
NKX3-2 Antibodies
NKX3-2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015849LA01HU | NKX3-2 Antibody | Human, Rat | ELISA, WB |
| CSB-PA015849LB01HU | NKX3-2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA015849LC01HU | NKX3-2 Antibody, FITC conjugated | Human |
NKX3-2 Proteins
NKX3-2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015849HU CSB-BP015849HU CSB-MP015849HU CSB-EP015849HU-B |
Recombinant Human Homeobox protein Nkx-3.2 (NKX3-2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP015849HU | Recombinant Human Homeobox protein Nkx-3.2 (Nkx3-2) | E.coli |
| CSB-EP015849HU2 | Recombinant Human Homeobox protein Nkx-3.2 (Nkx3-2), partial | E.coli |
| CSB-BP015849HU2 | Recombinant Human Homeobox protein Nkx-3.2 (Nkx3-2), partial | Baculovirus |
