NOX1
NOX1，全稱為NADPH氧化酶1，主要負責在細胞內生成少量活性氧分子，這些分子如同細胞內的“信號載體”，能調節細胞的生長、分化，以及細胞對外界刺激的反應——比如在腸道上皮細胞中，它幫助維持正常的屏障功能，還能參與免疫細胞的防御過程；在某些組織中，它也影響著細胞間的信息傳遞。
當NOX1活性失衡時，可能會打破細胞內的氧化狀態，與多種疾病相關：炎癥性腸病患者的腸道組織中常能檢測到它的活性升高；結直腸癌等腫瘤的進展，也可能和它的過度激活有關。目前針對NOX1的藥物研發處于實驗室階段，一些抑制劑被發現能有效調節其活性，為相關疾病的治療帶來新希望，但尚未進入臨床應用。
熱銷產品
Recombinant Human NADPH oxidase 1 (NOX1) (CSB-CF015959HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數據
Western blot analysis of 293T Hela VEC KB mouse-kidney 3T3 lysate, antibody was diluted at 2000. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-stomach, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-stomach, antibody was diluted at 1:200
NOX1 Antibodies
NOX1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA924751 | NOX1 Antibody | Human | ELISA,WB |
| CSB-PA008843 | NOX1 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA120772 | NOX1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA220321 | NOX1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA443876 | NOX1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA015959LA01HU | NOX1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA015959LB01HU | NOX1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA015959LC01HU | NOX1 Antibody, FITC conjugated | Human | |
| CSB-PA015959LD01HU | NOX1 Antibody, Biotin conjugated | Human | ELISA |
NOX1 Proteins
NOX1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015959MO1 CSB-EP015959MO1 CSB-BP015959MO1 CSB-MP015959MO1 CSB-EP015959MO1-B |
Recombinant Mouse NADPH oxidase 1 (Nox1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF015959MO | Recombinant Mouse NADPH oxidase 1 (Nox1) | in vitro E.coli expression system |
NOX1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015959RA1 CSB-EP015959RA1 CSB-BP015959RA1 CSB-MP015959RA1 CSB-EP015959RA1-B |
Recombinant Rat NADPH oxidase 1 (Nox1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF015959RA | Recombinant Rat NADPH oxidase 1 (Nox1) | in vitro E.coli expression system |
NOX1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015959HU1 CSB-EP015959HU1 CSB-BP015959HU1 CSB-MP015959HU1 CSB-EP015959HU1-B |
Recombinant Human NADPH oxidase 1 (NOX1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF015959HU | Recombinant Human NADPH oxidase 1 (NOX1) | in vitro E.coli expression system |
| CSB-MP015959HU | Recombinant Human NADPH oxidase 1 (NOX1)-VLPs | Mammalian cell |
