NTM

NTM，全稱為神經(jīng)抑素蛋白，常用別名神經(jīng)細(xì)胞黏附分子NTM，是一種糖基磷脂酰肌醇錨定型膜蛋白。它主要表達(dá)于中樞神經(jīng)系統(tǒng)，介導(dǎo)細(xì)胞間黏附連接，參與神經(jīng)發(fā)育、神經(jīng)突起生長以及神經(jīng)網(wǎng)絡(luò)構(gòu)建過程，對維持神經(jīng)系統(tǒng)正常結(jié)構(gòu)與生理功能十分重要。
NTM表達(dá)異常與神經(jīng)系統(tǒng)退行性疾病、精神類疾病密切相關(guān)，同時(shí)異常上調(diào)會促進(jìn)腦腫瘤細(xì)胞遷移侵襲，影響腫瘤預(yù)后。目前NTM多用于神經(jīng)系統(tǒng)疾病與腦腫瘤的預(yù)后標(biāo)志物研究，針對該蛋白功能調(diào)控的靶向小分子調(diào)節(jié)劑仍處于臨床前探索階段，通過改善神經(jīng)發(fā)育異常、抑制腫瘤惡性進(jìn)展，為神經(jīng)系統(tǒng)疾病及腦部腫瘤提供潛在全新治療思路。

熱銷產(chǎn)品

NTM Antibody (CSB-PA880111ESR1HU)

驗(yàn)證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA880111ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA880111ESR1HU at dilution of 1:100

NTM Antibody

NTM Protein

NTM Antibodies

NTM for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA833225	NTM Antibody	Human	ELISA,WB
CSB-PA003419	NTM Antibody	Human	WB, IHC, ELISA
CSB-PA880111ESR1HU	NTM Antibody	Human	ELISA, IHC
CSB-PA880111ESR2HU	NTM Antibody	Human, Mouse	ELISA, WB, IHC

NTM Proteins

NTM Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP016126HU CSB-EP016126HU CSB-BP016126HU CSB-MP016126HU CSB-EP016126HU-B	Recombinant Human Neurotrimin (NTM)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli