OSGEP
OSGEP ，全稱為 O - 唾液酸糖蛋白內肽酶，常見別名有 OSGEPL1、C14orf111、FLJ20203，是一類廣泛表達于人體多種組織的保守蛋白，屬于糖蛋白加工相關的蛋白酶家族。它主要參與糖蛋白的降解與加工過程，輔助維持細胞內蛋白穩(wěn)態(tài)，同時協(xié)同相關分子調控細胞正常生理活動，對機體代謝與組織穩(wěn)態(tài)的維持具有重要意義。
OSGEP功能異常與多種疾病密切相關，最典型的是吉爾斯綜合征，其功能缺陷會導致疾病相關癥狀發(fā)生，同時也與部分惡性腫瘤、神經(jīng)系統(tǒng)疾病相關，可作為疾病診斷與預后判斷的參考指標。目前相關研發(fā)聚焦于疾病診斷與靶向干預，相關檢測試劑正逐步優(yōu)化，針對其功能調控的候選藥物處于臨床前驗證階段，為相關疾病的精準診療提供了新方向。
熱銷產(chǎn)品
Recombinant Human tRNA N6-adenosine threonylcarbamoyltransferase (OSGEP) (CSB-EP878842HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
OSGEP Antibody (CSB-PA878842ESR1HU)
驗證數(shù)據(jù)
Western blot
All lanes: OSGEP antibody at 3.18µg/ml
Lane 1: 293T whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: Raji whole cell lysate
Lane 4: PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 36 kDa
Observed band size: 36 kDa
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA878842ESR1HU at dilution of 1:100
OSGEP Antibodies
OSGEP for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017256GA01HU | OSGEP Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA878842ESR1HU | OSGEP Antibody | Human | ELISA, WB, IHC |
| CSB-PA878842ESR2HU | OSGEP Antibody | Human | ELISA, WB, IHC |
OSGEP Proteins
OSGEP Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP878842HU CSB-BP878842HU CSB-MP878842HU CSB-EP878842HU-B |
Recombinant Human tRNA N6-adenosine threonylcarbamoyltransferase (OSGEP) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP878842HU | Recombinant Human tRNA N6-adenosine threonylcarbamoyltransferase (OSGEP) | E.coli |
