PNMA2
PNMA2，全稱為副腫瘤Ma抗原2，常用別名是Ma2，屬于副腫瘤抗原家族成員。它在人體正常組織中主要分布于睪丸、大腦等區域，而在某些腫瘤細胞中會出現異常表達，進而觸發機體的免疫應答。這種異常表達往往和副腫瘤神經綜合征相關聯，比如部分睪丸生殖細胞腫瘤、小細胞肺癌患者可能因此出現神經系統癥狀，像認知減退、肢體無力或癲癇發作等。
針對這類由PNMA2異常引發的病癥，目前臨床多采用免疫調節手段，比如使用糖皮質激素或免疫抑制劑來減輕免疫反應帶來的損傷；同時，也有研究團隊在探索靶向該蛋白的特異性抗體，期望能更精準地抑制腫瘤進展并緩解神經癥狀，但相關療法仍處于試驗階段，尚未成為常規治療方案。
熱銷產品
Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial (CSB-EP018267HUb1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PNMA2 Antibody (CSB-PA018267LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018267LA01HU at dilution of 1:100
PNMA2 Antibodies
PNMA2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018267GA01HU | PNMA2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA018267LA01HU | PNMA2 Antibody | Human | ELISA, IHC |
| CSB-PA018267LB01HU | PNMA2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018267LC01HU | PNMA2 Antibody, FITC conjugated | Human | |
| CSB-PA018267LD01HU | PNMA2 Antibody, Biotin conjugated | Human | ELISA |
PNMA2 Proteins
PNMA2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018267HU | Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | Yeast |
| CSB-EP018267HU | Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | E.coli |
| CSB-MP018267HU CSB-EP018267HU-B |
Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018267HUa2 | Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | E.coli |
| CSB-EP018267HUb1 | Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | E.coli |
| CSB-EP018267HUc7 | Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | E.coli |
| CSB-BP018267HU | Recombinant Human Paraneoplastic antigen Ma2 (PNMA2), partial | Baculovirus |
