PREP
PREP，全稱為脯氨酰內肽酶，常用別名是脯氨酸肽鏈內切酶。它廣泛分布于人體腦組織、肝臟與免疫細胞中，能夠特異性切割多肽鏈中脯氨酸位點，參與神經肽、激素等生物活性分子的加工與降解，對維持神經系統穩定和細胞正常代謝具有重要作用。
PREP表達或活性異常與多種疾病密切相關，在阿爾茨海默病、帕金森病等神經退行性疾病中表現尤為明顯，同時也與部分腫瘤增殖、炎癥反應存在關聯。目前針對PREP的抑制劑已成為藥物研發的重要方向，多款小分子化合物進入臨床前及早期臨床研究，通過調節其活性改善神經病變進程，為相關疾病治療提供了新的潛在策略。
熱銷產品
PITRM1 Antibody (CSB-PA692283ESR2HU)
驗證數據
Western blot
All lanes: PITRM1 antibody at 2.42μg/ml
Lane 1: Mouse placenta tissue
Lane 2: A549 whole cell lysate
Lane 3: Rat gonad tissue
Lane 4: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 118, 107 kDa
Observed band size: 118, 50 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA692283ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA692283ESR2HU at dilution of 1:100
PREP Antibodies
PREP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018041GA01HU | PITRM1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA018664GA01HU | PREP Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA692283ESR1HU | PITRM1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA692283ESR2HU | PITRM1 Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA018664LA01HU | PREP Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA018664LB01HU | PREP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018664LC01HU | PREP Antibody, FITC conjugated | Human | |
| CSB-PA018664LD01HU | PREP Antibody, Biotin conjugated | Human | ELISA |
PREP Proteins
PREP Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018664PI CSB-EP018664PI CSB-BP018664PI CSB-MP018664PI CSB-EP018664PI-B |
Recombinant Pig Prolyl endopeptidase (PREP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PREP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018664HU(A4) CSB-BP018664HU(A4) CSB-MP018664HU(A4) CSB-EP018664HU(A4)-B |
Recombinant Human Prolyl endopeptidase (PREP) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP692283HU CSB-EP692283HU CSB-BP692283HU CSB-MP692283HU CSB-EP692283HU-B |
Recombinant Human Presequence protease, mitochondrial (PITRM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018664HU | Recombinant Human Prolyl endopeptidase (PREP), partial | E.coli |
PREP Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018664RA CSB-EP018664RA CSB-BP018664RA CSB-MP018664RA CSB-EP018664RA-B |
Recombinant Rat Prolyl endopeptidase (Prep) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PREP Proteins for Dictyostelium discoideum (Slime mold)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018664DKK CSB-EP018664DKK CSB-BP018664DKK CSB-MP018664DKK CSB-EP018664DKK-B |
Recombinant Dictyostelium discoideum Prolyl endopeptidase (prep), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PREP Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018664MO CSB-BP018664MO CSB-MP018664MO CSB-EP018664MO-B |
Recombinant Mouse Prolyl endopeptidase (Prep) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PREP Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018664BO CSB-EP018664BO CSB-BP018664BO CSB-MP018664BO CSB-EP018664BO-B |
Recombinant Bovine Prolyl endopeptidase (PREP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
