PRSS1

PRSS1，即胰蛋白酶原1，也常被稱為胰蛋白酶原A，是胰腺外分泌細(xì)胞分泌的重要蛋白。它在胰腺中以無(wú)活性的酶原形式存在，隨胰液進(jìn)入小腸后，會(huì)被腸激酶激活為胰蛋白酶，幫助分解食物中的蛋白質(zhì)，維持正常的消化功能。
當(dāng)PRSS1基因發(fā)生突變時(shí)，這種酶原可能在胰腺內(nèi)部就提前激活，變成有活性的胰蛋白酶，開(kāi)始消化胰腺自身的組織，從而引發(fā)急性胰腺炎。遺傳性胰腺炎就與PRSS1的突變密切相關(guān)，患者往往反復(fù)出現(xiàn)胰腺炎發(fā)作，還可能增加胰腺癌的風(fēng)險(xiǎn)。目前針對(duì)這類由PRSS1異常導(dǎo)致的疾病，研究人員正在開(kāi)發(fā)能抑制異常激活的胰蛋白酶的藥物，比如一些小分子化合物，部分已進(jìn)入早期臨床試驗(yàn)，有望為患者提供新的治療選擇。

熱銷產(chǎn)品

Recombinant Human Serine protease 1 (PRSS1), partial (CSB-EP018811HU1)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PRSS1 Antibody (CSB-PA12309A0Rb)

驗(yàn)證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA12309A0Rb at dilution of 1:100

Human trypsin ELISA Kit (CSB-E09827h)

驗(yàn)證數(shù)據(jù)

貨號(hào)：CSB-E09827h

規(guī)格：96T/48T

靈敏度：15.6 ng/mL

檢測(cè)范圍：62.5 ng/mL-4000 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PRSS1 Antibody

PRSS1 Protein

PRSS1 ELISA Kit

PRSS1 Antibodies

PRSS1 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA004338	PRSS1 Antibody	Human	WB, ELISA
CSB-PA12309A0Rb	PRSS1 Antibody	Human	ELISA, IHC
CSB-PA12309B0Rb	PRSS1 Antibody, HRP conjugated	Human	ELISA
CSB-PA12309C0Rb	PRSS1 Antibody, FITC conjugated	Human
CSB-PA12309D0Rb	PRSS1 Antibody, Biotin conjugated	Human	ELISA

PRSS1 Proteins

PRSS1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-MP018811HU CSB-EP018811HU-B	Recombinant Human Serine protease 1 (PRSS1)	Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP018811HU	Recombinant Human Serine protease 1 (PRSS1)	E.coli
CSB-EP018811HU1	Recombinant Human Serine protease 1 (PRSS1), partial	E.coli
CSB-YP018811HU	Recombinant Human Serine protease 1 (PRSS1)	Yeast
CSB-BP018811HU	Recombinant Human Serine protease 1 (PRSS1)	Baculovirus