PTGDS
PTGDS，全稱為前列腺素D2合成酶，常被稱為腦型前列腺素D2合成酶（L-PGDS），是參與體內(nèi)前列腺素D2生成的重要蛋白。它在中樞神經(jīng)系統(tǒng)、生殖系統(tǒng)及免疫系統(tǒng)中廣泛分布：大腦里可調(diào)節(jié)睡眠周期與情緒狀態(tài)，生殖系統(tǒng)中參與精液液化過程，肺部和鼻腔黏膜處則與過敏反應(yīng)的發(fā)生密切相關(guān)。臨床研究發(fā)現(xiàn)，哮喘、過敏性鼻炎患者體內(nèi)PTGDS活性或表達(dá)水平往往異常升高，部分神經(jīng)退行性疾病也與它的功能失衡存在關(guān)聯(lián)。目前針對(duì)該蛋白的藥物研發(fā)正逐步推進(jìn)，一些抑制劑候選物已進(jìn)入早期臨床試驗(yàn)階段，有望為過敏性疾病及相關(guān)神經(jīng)疾病提供新的治療選擇。
熱銷產(chǎn)品
Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS) (CSB-EP018969HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PTGDS Antibody (CSB-PA018969HA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA018969HA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA018969HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Prostaglandin-H2 D-isomerase(PTGDS) ELISA kit (CSB-EL018969HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL018969HU
規(guī)格：96T/48T
靈敏度：0.195 ng/mL
檢測(cè)范圍：0.78 ng/mL-50 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
PTGDS Antibodies
PTGDS for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA018969GA01HU | PTGDS Antibody | Human | ELISA,WB,IHC |
| CSB-PA018969HA01HU | PTGDS Antibody | Human | ELISA, IHC, IF |
| CSB-PA018969HB01HU | PTGDS Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018969HC01HU | PTGDS Antibody, FITC conjugated | Human | |
| CSB-PA018969HD01HU | PTGDS Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA191275 | PTGDS Antibody | Human | ELISA,IHC |
PTGDS Proteins
PTGDS Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018969HU CSB-BP018969HU CSB-MP018969HU CSB-EP018969HU-B |
Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018969HU | Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS) | E.coli |
| CSB-EP018969HU(M) | Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS) (145-156:MATLYSRTQTPR→Missing) | E.coli |
| CSB-EP018969HU(M1) | Recombinant Human Prostaglandin-H2 D-isomerase (PTGDS)(176-185:TIVFLPQTDK→Missing) | E.coli |
PTGDS ELISA Kit
PTGDS ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL018969HU | Human Prostaglandin-H2 D-isomerase(PTGDS) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 0.195 ng/mL |
