PUS7L
PUS7L，全稱為假尿苷合酶7樣蛋白，它是細胞內假尿苷合酶相關蛋白，廣泛表達于人體各類組織，參與RNA假尿苷修飾、RNA穩定性調控，假尿苷修飾對RNA功能、基因表達調控具有重要意義，維持細胞正常轉錄翻譯過程。 PUS7L功能異常與RNA修飾異常及多種疾病相關，功能缺陷會導致RNA穩定性下降、基因表達紊亂，與神經退行性疾病、發育遲緩相關；異常表達也與腫瘤相關，參與腫瘤細胞RNA代謝重編程，促進腫瘤增殖。目前針對PUS7L的研究處于基礎階段，靶向調控制劑處于臨床前探索，為相關疾病提供潛在治療方向。
熱銷產品
Recombinant Human Pseudouridylate synthase PUS7L (PUS7L) (CSB-EP867121HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PUS7L Proteins
PUS7L Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP867121HU CSB-MP867121HU CSB-EP867121HU-B |
Recombinant Human Pseudouridylate synthase 7 homolog-like protein (PUS7L) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP867121HU | Recombinant Human Pseudouridylate synthase PUS7L (PUS7L) | E.coli |
| CSB-BP867121HU | Recombinant Human Pseudouridylate synthase PUS7L (PUS7L) | Baculovirus |
