Prg4

PRG4，全稱為蛋白聚糖4，常用別名是潤滑素，也被稱作關節滑液蛋白2。它主要分布在關節滑液與軟骨表面，是維持關節正常活動的關鍵物質之一——能減少骨骼間的摩擦，保護軟骨免受過度磨損，讓關節保持靈活順滑。當Prg4含量不足或功能異常時，關節易出現磨損加重、炎癥反應，常見的骨關節炎就與它的異常相關，部分遺傳性關節疾病也和它有關聯。
目前針對它的治療探索不少：直接補充潤滑素的制劑已進入臨床試驗階段，用于緩解關節炎患者的疼痛并改善關節功能；還有研究在開發能促進身體自身生成更多潤滑素的藥物，助力受損關節組織的修復，這些進展為關節疾病的治療提供了新的思路。

熱銷產品

Recombinant Human Proteoglycan 4 (PRG4), partial (CSB-YP018672HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PRG4 Antibody (CSB-PA018672LA01HU)

驗證數據

IHC image of CSB-PA018672LA01HU diluted at 1:200 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

Human proteoglycan 4(PRG4) ELISA Kit (CSB-E14124h)

驗證數據

貨號：CSB-E14124h

規格：96T/48T

靈敏度：1.56 ng/ml

檢測范圍：3.12 ng/ml-200 ng/ml

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Prg4 Antibody

Prg4 Protein

Prg4 ELISA Kit

Prg4 Antibodies

Prg4 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA018672LA01HU	PRG4 Antibody	Human	ELISA, IHC
CSB-PA018672LB01HU	PRG4 Antibody, HRP conjugated	Human	ELISA
CSB-PA018672LC01HU	PRG4 Antibody, FITC conjugated	Human
CSB-PA018672LD01HU	PRG4 Antibody, Biotin conjugated	Human	ELISA

Prg4 Proteins

Prg4 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-EP018672HU CSB-BP018672HU CSB-MP018672HU CSB-EP018672HU-B	Recombinant Human Proteoglycan 4 (PRG4), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP018672HU	Recombinant Human Proteoglycan 4 (PRG4), partial	Yeast
CSB-BP018672HU	Recombinant Human Proteoglycan 4 (PRG4), partial	Baculovirus