RAB10
RAB10，全稱為RAB家族GTP酶10，常用別名小GTP酶RAB10。它是細(xì)胞內(nèi)重要的囊泡轉(zhuǎn)運(yùn)調(diào)控蛋白，廣泛表達(dá)于人體各類組織，參與細(xì)胞內(nèi)囊泡形成、轉(zhuǎn)運(yùn)及融合過程，調(diào)控蛋白質(zhì)、脂質(zhì)等物質(zhì)的胞內(nèi)運(yùn)輸，維持細(xì)胞正常物質(zhì)代謝與信號(hào)傳遞。 RAB10異常表達(dá)與多種疾病密切相關(guān)，功能紊亂會(huì)導(dǎo)致囊泡轉(zhuǎn)運(yùn)異常，與糖尿病、神經(jīng)退行性疾病、心血管疾病相關(guān)，同時(shí)在肺癌、乳腺癌等腫瘤中異常高表達(dá)，促進(jìn)腫瘤細(xì)胞物質(zhì)轉(zhuǎn)運(yùn)與侵襲轉(zhuǎn)移。目前RAB10靶向抑制劑處于臨床前研究階段，通過調(diào)控囊泡轉(zhuǎn)運(yùn)，為代謝疾病、神經(jīng)疾病及腫瘤提供新型干預(yù)方案。
熱銷產(chǎn)品
Recombinant Human Ras-related protein Rab-10 (RAB10) (CSB-YP019152HU(A4))
驗(yàn)證數(shù)據(jù)
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
RAB10 Recombinant Monoclonal Antibody (CSB-RA898224A0HU)
驗(yàn)證數(shù)據(jù)
Western blotting analysis using RAB10 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with RAB10 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
RAB10 Antibody (CSB-PA019152LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA019152LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA019152LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA019152LA01HU at dilution of 1:100
Human Ras-related protein Rab-10(RAB10) ELISA kit (CSB-EL019152HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL019152HU
規(guī)格：96T/48T
靈敏度：9.77 pg/mL
檢測(cè)范圍：39 pg/mL-2500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
RAB10 Antibodies
RAB10 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA019152LD01HU | RAB10 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA019152GA01HU | RAB10 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA019152LC01HU | RAB10 Antibody, FITC conjugated | Human | |
| CSB-PA019152LA01HU | RAB10 Antibody | Human | ELISA, IHC, IF |
| CSB-RA898224A0HU | RAB10 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB |
RAB10 Proteins
RAB10 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019152RA CSB-EP019152RA CSB-BP019152RA CSB-MP019152RA CSB-EP019152RA-B |
Recombinant Rat Ras-related protein Rab-10 (Rab10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB10 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019152DO CSB-EP019152DO CSB-BP019152DO CSB-MP019152DO CSB-EP019152DO-B |
Recombinant Dog Ras-related protein Rab-10 (RAB10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB10 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019152HU CSB-BP019152HU CSB-MP019152HU CSB-EP019152HU-B |
Recombinant Human Ras-related protein Rab-10 (RAB10) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019152HU | Recombinant Human Ras-related protein Rab-10 (RAB10), partial | E.coli |
| CSB-BP019152HU(A4)b1 | Recombinant Human Ras-related protein Rab-10 (RAB10) | Baculovirus |
| CSB-YP019152HU(A4) | Recombinant Human Ras-related protein Rab-10 (RAB10) | Yeast |
RAB10 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019152MO CSB-BP019152MO CSB-MP019152MO CSB-EP019152MO-B |
Recombinant Mouse Ras-related protein Rab-10 (Rab10) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019152MO | Recombinant Mouse Ras-related protein Rab-10 (Rab10) | E.coli |
| CSB-EP019152MOa0 | Recombinant Mouse Ras-related protein Rab-10 (Rab10) | E.coli |
RAB10 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP712836PYX CSB-EP712836PYX CSB-BP712836PYX CSB-MP712836PYX CSB-EP712836PYX-B |
Recombinant Pongo abelii Ras-related protein Rab-10 (RAB10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB10 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP736561CH CSB-EP736561CH CSB-BP736561CH CSB-MP736561CH CSB-EP736561CH-B |
Recombinant Chicken Ras-related protein Rab-10 (RAB10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB10 ELISA Kit
RAB10 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL019152HU | Human Ras-related protein Rab-10(RAB10) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 9.77 pg/mL |
