RORA
RORA，全稱為維甲酸相關孤兒受體α，常被簡稱為ROR-alpha。它是身體里一種關鍵的調節分子，既能參與維持日常作息節律的穩定，讓睡眠與覺醒的周期保持規律；也會影響免疫細胞的功能狀態，幫助免疫系統維持平衡，避免過度反應或反應不足。
當RORA活性出現異常時，可能和多種疾病相關：比如多發性硬化這類自身免疫疾病，患者體內該蛋白的水平或功能往往存在改變；此外，睡眠紊亂、代謝綜合征（如肥胖、血糖異常）等問題也可能與它的調節失衡有關。目前針對該蛋白的藥物研發還在推進中，一些激活劑類化合物正在實驗室或早期臨床研究階段，嘗試通過增強其活性來緩解自身免疫病的炎癥反應，或改善代謝與節律相關的健康問題，但尚未有成熟藥物上市。
熱銷產品
Recombinant Human Nuclear receptor ROR-alpha (RORA) (CSB-EP020069HUa0)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
RORA Antibody (CSB-PA020069LA01HU)
驗證數據
Western Blot
Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, PC-3 whole cell lysate, Mouse liver tissue
All lanes: RORA antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 64, 62, 54 kDa
Observed band size: 59 kDa
RORA Antibodies
RORA for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA020069GA01HU | RORA Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004020 | RORA Antibody | Human,Monkey | WB, IHC, IF, ELISA |
| CSB-PA182231 | RORA Antibody | Human | ELISA,WB |
| CSB-PA020069LA01HU | RORA Antibody | Human, Mouse | ELISA, WB |
| CSB-PA020069LB01HU | RORA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020069LC01HU | RORA Antibody, FITC conjugated | Human | |
| CSB-PA020069LD01HU | RORA Antibody, Biotin conjugated | Human | ELISA |
RORA Proteins
RORA Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020069HU1(F1) | Recombinant Human Nuclear receptor ROR-alpha (RORA),Partial | Yeast |
| CSB-EP020069HU CSB-MP020069HU CSB-EP020069HU-B |
Recombinant Human Nuclear receptor ROR-alpha (RORA),Partial | E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP020069HU | Recombinant Human Nuclear receptor ROR-alpha (RORA) | Baculovirus |
| CSB-EP020069HUa0 | Recombinant Human Nuclear receptor ROR-alpha (RORA) | E.coli |
RORA Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020069MO CSB-EP020069MO CSB-BP020069MO CSB-MP020069MO CSB-EP020069MO-B |
Recombinant Mouse Nuclear receptor ROR-alpha (Rora) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
