哎呀哎呀在线观看视频|狼狼鲁色在线视频播放|天天躁日日躁狠狠躁欧美老妇|波斯女人1977满天星|九阳真经未满十八岁能学吗|被老外做的都肿了|7tv影院

Your Good Partner in Biology Research

RPTOR

Regulatory-associated protein of mTOR is a protein in humans that is encoded by RPTOR gene. Involved in the control of the mammalian target of rapamycin complex 1 (mTORC1) activity which regulates cell growth and survival, and autophagy in response to nutrient and hormonal signals; functions as a scaffold for recruiting mTORC1 substrates. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.

RPTOR Antibodies

RPTOR for Homo sapiens (Human)

RPTOR Proteins

RPTOR Proteins for Mus musculus (Mouse)

RPTOR Proteins for Homo sapiens (Human)



×