S1PR2
S1PR2，全稱為鞘氨醇-1-磷酸受體2，常用別名S1P受體2。它是細胞膜上的G蛋白偶聯受體，廣泛表達于免疫細胞、心血管系統及神經系統，參與鞘氨醇-1-磷酸介導的信號傳導，調控細胞遷移、增殖、凋亡及免疫平衡，對心血管穩態、免疫功能及神經系統發育具有重要作用。 S1PR2異常表達與多種疾病密切相關，異常活化會導致免疫失衡、血管異常，與自身免疫病、心血管疾病相關；同時在腫瘤中異常表達，參與腫瘤免疫微環境調控，影響腫瘤細胞凋亡。目前S1PR2調節劑處于臨床前研究階段，通過調控其信號傳導，為免疫疾病、心血管疾病及腫瘤提供治療思路。
熱銷產品
Recombinant Human Sphingosine 1-phosphate receptor 2 (S1PR2) (CSB-CF020651HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
S1PR2 Antibody (CSB-PA020651LA01HU)
驗證數據
Western Blot
Positive WB detected in: Hela whole cell lysate(30μg), MCF-7 whole cell lysate(30μg), SY5Y whole cell lysate(30μg), 293 whole cell lysate(30μg),HT29 whole cell lysate(30μg),Mouse Heart tissue lysate(30μg),Rat Heart tissue lysate(30μg)
All lanes: S1PR2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 39, 40-50 kDa
Observed band size: 40 kDa
Exposure time: 120s
S1PR2 Antibodies
S1PR2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA020651GA01HU | S1PR2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA002249 | S1PR2 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA070283 | S1PR2 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA225608 | S1PR2 Antibody | Human | ELISA,IHC |
| CSB-PA020651LA01HU | S1PR2 Antibody | Human,Mouse,Rat | ELISA, WB |
| CSB-PA020651LB01HU | S1PR2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020651LC01HU | S1PR2 Antibody, FITC conjugated | Human | |
| CSB-PA020651LD01HU | S1PR2 Antibody, Biotin conjugated | Human | ELISA |
S1PR2 Proteins
S1PR2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020651RA1 CSB-EP020651RA1 CSB-BP020651RA1 CSB-MP020651RA1 CSB-EP020651RA1-B |
Recombinant Rat Sphingosine 1-phosphate receptor 2 (S1pr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020651RA | Recombinant Rat Sphingosine 1-phosphate receptor 2 (S1pr2) | in vitro E.coli expression system |
S1PR2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020651MO1 CSB-EP020651MO1 CSB-BP020651MO1 CSB-MP020651MO1 CSB-EP020651MO1-B |
Recombinant Mouse Sphingosine 1-phosphate receptor 2 (S1pr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020651MO | Recombinant Mouse Sphingosine 1-phosphate receptor 2 (S1pr2) | in vitro E.coli expression system |
S1PR2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020651HU1 CSB-EP020651HU1 CSB-BP020651HU1 CSB-MP020651HU1 CSB-EP020651HU1-B |
Recombinant Human Sphingosine 1-phosphate receptor 2 (S1PR2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020651HU | Recombinant Human Sphingosine 1-phosphate receptor 2 (S1PR2) | in vitro E.coli expression system |
S1PR2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP884843DIL1 CSB-EP884843DIL1 CSB-BP884843DIL1 CSB-MP884843DIL1 CSB-EP884843DIL1-B |
Recombinant Danio rerio Sphingosine 1-phosphate receptor 2 (s1pr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF884843DIL | Recombinant Danio rerio Sphingosine 1-phosphate receptor 2 (s1pr2) | in vitro E.coli expression system |
