S1PR5
S1PR5，全稱為鞘氨醇-1-磷酸受體5，常用別名S1P受體5。它是細(xì)胞膜上的G蛋白偶聯(lián)受體，主要表達(dá)于神經(jīng)系統(tǒng)、免疫細(xì)胞及心血管系統(tǒng)，參與鞘氨醇-1-磷酸介導(dǎo)的信號(hào)傳導(dǎo)，調(diào)控細(xì)胞遷移、增殖、凋亡及免疫平衡，對(duì)神經(jīng)系統(tǒng)穩(wěn)態(tài)、免疫功能及血管發(fā)育具有重要作用。 S1PR5異常表達(dá)與神經(jīng)系統(tǒng)疾病及腫瘤密切相關(guān)，表達(dá)不足會(huì)影響神經(jīng)細(xì)胞遷移及信號(hào)傳遞，與多發(fā)性硬化癥等神經(jīng)疾病相關(guān)；異常高表達(dá)則與肺癌、淋巴瘤等腫瘤相關(guān)，促進(jìn)腫瘤細(xì)胞增殖、侵襲。目前S1PR5調(diào)節(jié)劑處于臨床前研究階段，通過調(diào)控其信號(hào)傳導(dǎo)，為神經(jīng)疾病及腫瘤提供治療思路。
熱銷產(chǎn)品
Recombinant Human Sphingosine 1-phosphate receptor 5 (S1PR5) (CSB-CF867132HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
S1PR5 Antibody (CSB-PA867132LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: HEK293 whole cell lysate, Jurkat whole cell lysate, Mouse heart tissue
All lanes: S1PR5 antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 42, 33 kDa
Observed band size: 42 kDa
Immunofluorescent analysis of A549 cells using CSB-PA867132LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
S1PR5 Antibodies
S1PR5 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA020654GA01HU | S1PR5 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA030092 | S1PR5 Antibody | Human | IHC, IF, ELISA |
| CSB-PA971344 | S1PR5 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA867132LA01HU | S1PR5 Antibody | Human, Mouse | ELISA, WB, IF |
| CSB-PA867132LB01HU | S1PR5 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA867132LC01HU | S1PR5 Antibody, FITC conjugated | Human | |
| CSB-PA867132LD01HU | S1PR5 Antibody, Biotin conjugated | Human | ELISA |
S1PR5 Proteins
S1PR5 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP718065PI1 CSB-EP718065PI1 CSB-BP718065PI1 CSB-MP718065PI1 CSB-EP718065PI1-B |
Recombinant Pig Sphingosine 1-phosphate receptor 5 (S1PR5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF718065PI | Recombinant Pig Sphingosine 1-phosphate receptor 5 (S1PR5) | in vitro E.coli expression system |
S1PR5 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP838693MO1 CSB-BP838693MO1 CSB-MP838693MO1 CSB-EP838693MO1-B |
Recombinant Mouse Sphingosine 1-phosphate receptor 5 (S1pr5), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF838693MO | Recombinant Mouse Sphingosine 1-phosphate receptor 5 (S1pr5) | in vitro E.coli expression system |
S1PR5 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP864355RA1 CSB-EP864355RA1 CSB-BP864355RA1 CSB-MP864355RA1 CSB-EP864355RA1-B |
Recombinant Rat Sphingosine 1-phosphate receptor 5 (S1pr5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF864355RA | Recombinant Rat Sphingosine 1-phosphate receptor 5 (S1pr5) | in vitro E.coli expression system |
S1PR5 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP867132HU1 CSB-BP867132HU1 CSB-MP867132HU1 CSB-EP867132HU1-B |
Recombinant Human Sphingosine 1-phosphate receptor 5 (S1PR5), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF867132HU | Recombinant Human Sphingosine 1-phosphate receptor 5 (S1PR5) | in vitro E.coli expression system |
| CSB-EP867132HU1 | Recombinant Human Sphingosine 1-phosphate receptor 5 (S1PR5), partial | E.coli |
