SELENOP
SELENOP，即硒蛋白P，是人體內(nèi)負(fù)責(zé)硒元素轉(zhuǎn)運(yùn)的關(guān)鍵蛋白，常被簡(jiǎn)稱為SeP。它主要由肝臟合成并釋放入血，承載著血液中大部分的硒，將其輸送到大腦、睪丸等對(duì)硒需求較高的組織，保障這些部位的硒供應(yīng)與功能穩(wěn)定。
SELENOP水平與人體健康緊密相關(guān)：若硒蛋白P不足，易導(dǎo)致全身硒代謝失衡，不僅可能引發(fā)克山病這類硒缺乏相關(guān)的地方性疾病，還可能增加阿爾茨海默病等神經(jīng)退行性疾病的發(fā)生風(fēng)險(xiǎn)。目前臨床中常通過檢測(cè)血漿硒蛋白P含量來(lái)評(píng)估人體硒營(yíng)養(yǎng)狀態(tài)，指導(dǎo)硒補(bǔ)充干預(yù)；針對(duì)它的藥物研發(fā)尚處于早期階段，多聚焦于調(diào)節(jié)其表達(dá)以改善硒代謝異常，為相關(guān)疾病的防治提供新的思路。
熱銷產(chǎn)品
Recombinant Human Selenoprotein P (SELENO) (CSB-EP021018HUc7)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SELENOP Antibody (CSB-PA021018LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Mouse heart tissue, Mouse brain tissue, Mouse liver tissue
All lanes: SEPP1 antibody at 1：2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43 kDa
Observed band size: 43, 40 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA021018LA01HU at dilution of 1:100
Human Selenoprotein P(SEPP1) ELISA kit (CSB-EL021018HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL021018HU
規(guī)格：96T/48T
靈敏度：0.039 ng/mL
檢測(cè)范圍：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
SELENOP Antibodies
SELENOP for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA021018LB01HU | SELENOP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA021018LD01HU | SELENOP Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA021018LA01HU | SELENOP Antibody | Human, Mouse | ELISA, WB, IHC Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| CSB-PA553505 | SEPP1 Antibody | Human | ELISA,IHC |
| CSB-PA583633 | SEPP1 Antibody | Human | ELISA,IHC |
SELENOP Proteins
SELENOP Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP021018HU | Recombinant Human Selenoprotein P (SELENOP) (U59S,U300S,U318S,U330S,U345S,U352S,U367S,U369S,U376S,U378S) | Yeast |
| CSB-EP021018HU | Recombinant Human Selenoprotein P (SELENOP) (U59S,U300S,U318S,U330S,U345S,U352S,U367S,U369S,U376S,U378S) | E.coli |
| CSB-BP021018HU CSB-MP021018HU |
Recombinant Human Selenoprotein P (SELENOP) (U59S,U300S,U318S,U330S,U345S,U352S,U367S,U369S,U376S,U378S) | Baculovirus Mammalian cell |
| CSB-EP021018HUc7 | Recombinant Human Selenoprotein P (SELENO) | E.coli |
SELENOP ELISA Kit
SELENOP ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL021018HU | Human Selenoprotein P(SEPP1) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates, urine | 0.039 ng/mL |
