SEMA3C
SEMA3C，全稱為軸突導向因子3C，常用別名語義素3C。它是一種分泌型軸突導向蛋白，主要表達于神經系統、心血管系統及腫瘤組織，參與神經軸突導向、血管新生、細胞遷移及腫瘤微環境調控，對神經系統發育、血管穩態及腫瘤進展具有重要作用。 SEMA3C異常高表達與多種惡性腫瘤密切相關，在肺癌、乳腺癌、膠質瘤等腫瘤中顯著升高，能夠促進腫瘤血管新生、侵襲轉移及上皮間質轉化，提示患者預后不良。目前SEMA3C阻斷劑處于臨床前研究階段，通過抑制其促血管新生及侵襲作用，為實體腫瘤提供新型治療策略。
熱銷產品
SEMA3C Antibody (CSB-PA860786LA01HU)
驗證數據
IHC image of CSB-PA860786LA01HU diluted at 1:500 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
SEMA3C Antibodies
SEMA3C for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA020982GA01HU | SEMA3C Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA006602 | SEMA3C Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA860786LA01HU | SEMA3C Antibody | Human | ELISA, IHC |
| CSB-PA860786LB01HU | SEMA3C Antibody, HRP conjugated | Human | ELISA |
| CSB-PA860786LC01HU | SEMA3C Antibody, FITC conjugated | Human | |
| CSB-PA860786LD01HU | SEMA3C Antibody, Biotin conjugated | Human | ELISA |
SEMA3C Proteins
SEMA3C Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP860786HU CSB-EP860786HU CSB-BP860786HU CSB-MP860786HU CSB-EP860786HU-B |
Recombinant Human Semaphorin-3C (SEMA3C) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
