SEPSECS
SEPSECS，全稱為硒代半胱氨酸合酶，也常被簡稱為硒半胱氨酸合成酶。它在人體氨基酸代謝中發揮關鍵作用，主要負責將絲氨酸轉化為硒代半胱氨酸——這是一種含硒的特殊氨基酸，能被整合到特定蛋白質里，賦予這些蛋白獨特的生理功能。
SEPSECS蛋白功能異常時，可能會影響含硒蛋白的正常生成，進而引發健康問題。已有研究發現，SEPSECS相關的基因變化與某些神經系統疾病相關，比如部分遺傳性腦白質病變患者存在該蛋白功能缺陷，表現出運動發育遲緩、認知障礙等癥狀。目前針對這類問題的藥物研發仍處于早期階段，主要聚焦于探索補充硒元素或調節相關代謝過程來緩解癥狀，但尚未有成熟藥物應用于臨床。
熱銷產品
Recombinant Human O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS) (CSB-YP888032HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SEPSECS Antibody (CSB-PA14389A0Rb)
驗證數據
Western blot
All lanes: SEPSECS antibody at 2µg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56, 6 kDa
Observed band size: 56 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA14389A0Rb at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using CSB-PA14389A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
SEPSECS Antibodies
SEPSECS for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA021019GA01HU | SEPSECS Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA14389A0Rb | SEPSECS Antibody | Human | ELISA, WB, IHC, IF |
SEPSECS Proteins
SEPSECS Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP725367PYX CSB-EP725367PYX CSB-BP725367PYX CSB-MP725367PYX CSB-EP725367PYX-B |
Recombinant Pongo abelii O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SEPSECS Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-BP888032HU CSB-MP888032HU CSB-EP888032HU-B |
Recombinant Human O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP888032HU1 | Recombinant Human O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS), partial | E.coli |
| CSB-YP888032HU | Recombinant Human O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS) | Yeast |
| CSB-EP888032HU | Recombinant Human O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS) | E.coli |
