SLC23A2
SLC23A2，全稱為溶質(zhì)載體家族23成員2蛋白，常用別名是SVCT2。它主要負(fù)責(zé)維生素C在細(xì)胞間的轉(zhuǎn)運(yùn)，尤其在血腦屏障、視網(wǎng)膜及神經(jīng)組織中扮演關(guān)鍵角色——這些部位無法通過簡(jiǎn)單擴(kuò)散獲取維生素C，需依賴該蛋白將其主動(dòng)輸送至細(xì)胞內(nèi)，以維持抗氧化平衡，保護(hù)細(xì)胞免受自由基的侵害。
SLC23A2功能異常，可能導(dǎo)致維生素C在特定組織中缺乏，進(jìn)而與神經(jīng)系統(tǒng)發(fā)育障礙、年齡相關(guān)性黃斑變性等疾病相關(guān)。在藥物研發(fā)領(lǐng)域，研究人員正探索通過靶向該蛋白來提高組織內(nèi)維生素C水平，為癌癥（如增強(qiáng)化療效果）、神經(jīng)退行性疾病等的治療提供新策略，目前已有一些前期實(shí)驗(yàn)顯示出潛在的應(yīng)用價(jià)值。
熱銷產(chǎn)品
Recombinant Human Solute carrier family 23 member 2 (SLC23A2) (CSB-CF866221HU(A4)c7)
驗(yàn)證數(shù)據(jù)
c7-SDS.jpg)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SLC23A2 Antibody (CSB-PA866221LA01HU)
驗(yàn)證數(shù)據(jù)
Immunofluorescence staining of HepG2 cells with CSB-PA866221LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SLC23A2 Antibodies
SLC23A2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA866221DSR2HU | SLC23A2 Antibody | Human | ELISA, WB, IHC |
| CSB-PA866221LA01HU | SLC23A2 Antibody | Human | ELISA, IF |
SLC23A2 Proteins
SLC23A2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP866221HU CSB-EP866221HU CSB-BP866221HU CSB-MP866221HU CSB-EP866221HU-B |
Recombinant Human Solute carrier family 23 member 2 (SLC23A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF866221HU(A4) | Recombinant Human Solute carrier family 23 member 2 (SLC23A2) | in vitro E.coli expression system |
| CSB-MP866221HU(A4) | Recombinant Human Solute carrier family 23 member 2 (SLC23A2)-VLPs | Mammalian cell |
| CSB-CF866221HU(A4)c7 | Recombinant Human Solute carrier family 23 member 2 (SLC23A2) | in vitro E.coli expression system |
