SLC25A4
SLC25A4，全稱為溶質(zhì)載體家族25成員4，常用別名腺苷酸轉(zhuǎn)運(yùn)蛋白。它是定位于線粒體膜上的轉(zhuǎn)運(yùn)蛋白，廣泛表達(dá)于人體各類組織，參與線粒體與細(xì)胞質(zhì)間腺苷酸的轉(zhuǎn)運(yùn)，維持線粒體能量代謝穩(wěn)態(tài)，保障細(xì)胞正常能量供應(yīng)，對(duì)機(jī)體代謝、細(xì)胞存活具有關(guān)鍵作用。 SLC25A4功能缺陷或表達(dá)不足會(huì)導(dǎo)致線粒體能量代謝異常，腺苷酸轉(zhuǎn)運(yùn)障礙，引發(fā)線粒體病、神經(jīng)肌肉疾病、心肌病等，表現(xiàn)為肌肉無力、能量代謝障礙等癥狀；異常表達(dá)也與腫瘤相關(guān)，通過調(diào)節(jié)線粒體代謝，促進(jìn)腫瘤細(xì)胞增殖。目前SLC25A4修復(fù)制劑處于臨床前研究階段，為線粒體相關(guān)疾病及腫瘤提供治療思路。
熱銷產(chǎn)品
Recombinant Human ADP/ATP translocase 1 (SLC25A4) (CSB-CF021510HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SLC25A4 Antibody (CSB-PA021510LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA021510LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA021510LA01HU at dilution of 1:100
Immunofluorescence staining of PC-3 cells with CSB-PA021510LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SLC25A4 Antibodies
SLC25A4 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA021510GA01HU | SLC25A4 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA898234 | SLC25A4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA021510LA01HU | SLC25A4 Antibody | Human | ELISA, IHC, IF |
| CSB-PA021510LD01HU | SLC25A4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA021510LB01HU | SLC25A4 Antibody, HRP conjugated | Human | ELISA |
SLC25A4 Proteins
SLC25A4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021510HU1 CSB-EP021510HU1 CSB-BP021510HU1 CSB-MP021510HU1 CSB-EP021510HU1-B |
Recombinant Human ADP/ATP translocase 1 (SLC25A4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF021510HU | Recombinant Human ADP/ATP translocase 1 (SLC25A4) | in vitro E.coli expression system |
| CSB-MP021510HU | Recombinant Human ADP/ATP translocase 1 (SLC25A4)-VLPs | Mammalian cell |
SLC25A4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021510MO1 CSB-EP021510MO1 CSB-BP021510MO1 CSB-MP021510MO1 CSB-EP021510MO1-B |
Recombinant Mouse ADP/ATP translocase 1 (Slc25a4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF021510MO | Recombinant Mouse ADP/ATP translocase 1 (Slc25a4) | in vitro E.coli expression system |
SLC25A4 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021510BO1 CSB-EP021510BO1 CSB-BP021510BO1 CSB-MP021510BO1 CSB-EP021510BO1-B |
Recombinant Bovine ADP/ATP translocase 1 (SLC25A4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF021510BO | Recombinant Bovine ADP/ATP translocase 1 (SLC25A4) | in vitro E.coli expression system |
SLC25A4 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021510RB1 CSB-EP021510RB1 CSB-BP021510RB1 CSB-MP021510RB1 CSB-EP021510RB1-B |
Recombinant Rabbit ADP/ATP translocase 1 (SLC25A4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF021510RB | Recombinant Rabbit ADP/ATP translocase 1 (SLC25A4) | in vitro E.coli expression system |
SLC25A4 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021510RA1 CSB-EP021510RA1 CSB-BP021510RA1 CSB-MP021510RA1 CSB-EP021510RA1-B |
Recombinant Rat ADP/ATP translocase 1 (Slc25a4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF021510RA | Recombinant Rat ADP/ATP translocase 1 (Slc25a4) | in vitro E.coli expression system |
