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SSTR1

SSTR1,全稱為生長抑素受體1,常被簡稱為SST1R。它是一類分布于人體神經系統、內分泌器官及部分腫瘤組織的受體蛋白,能與生長抑素結合并發揮作用。兩者結合后,可調節細胞生長節奏與激素分泌,比如抑制胰島素、胰高血糖素等激素的釋放,也能減緩異常細胞的增殖速度。
在疾病領域,神經內分泌腫瘤、胰腺癌等疾病中常存在SSTR1表達的異常,部分腫瘤細胞會過度表達SSTR1,使其成為治療這些疾病的潛在靶點。藥物研發方面,已有長效肽類類似物可作用于包括SSTR1在內的生長抑素受體家族,用于控制腫瘤生長或緩解激素過多引發的癥狀;同時,針對SSTR1的小分子靶向藥物也在研發中,期望能更精準地發揮治療效果,改善患者預后。

熱銷產品

Recombinant Human Somatostatin receptor type 1 (SSTR1)-VLPs (CSB-MP022724HU)

驗證數據

CSB-MP022724HU

CSB-MP022724HU is detected by Mouse anti-6*His monoclonal antibody.

SSTR1 Antibody (CSB-PA793008)

驗證數據

CSB-PA793008

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA793008(SSTR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA793008

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA793008(SSTR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

SSTR1 Antibodies

SSTR1 for Homo sapiens (Human)

SSTR1 Proteins

SSTR1 Proteins for Rattus norvegicus (Rat)

SSTR1 Proteins for Homo sapiens (Human)

SSTR1 Proteins for Mus musculus (Mouse)

SSTR1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)



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