SSTR3
SSTR3，即生長抑素受體3，屬于生長抑素受體家族成員，常見別名包括SSTR3型受體。它在大腦海馬區、胰腺胰島細胞等部位分布較多，能與生長抑素結合，進而影響細胞的多種生理活動——比如調節激素釋放節奏、控制細胞增殖狀態。在一些疾病場景下，它的狀態會發生異常：部分神經內分泌腫瘤患者體內該受體表達明顯升高，成為疾病監測和干預的潛在靶點；而阿爾茨海默病患者大腦中，SSTR3功能可能受損，間接影響認知相關的細胞活動。目前針對它的藥物研發已有進展，一些肽類激動劑可模擬生長抑素的作用，通過與該受體結合抑制腫瘤細胞生長，部分候選藥物已進入臨床試驗階段，為相關疾病的治療帶來新的可能。
熱銷產品
Recombinant Human Somatostatin receptor type 3 (SSTR3)-VLPs (CSB-MP022726HU)
驗證數據
CSB-MP022726HU is detected by Mouse anti-6*His monoclonal antibody.
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA130335(SSTR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA130335(SSTR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
SSTR3 Antibodies
SSTR3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA130335 | SSTR3 Antibody | Human | ELISA,IHC |
| CSB-PA597067 | SSTR3 Antibody | Human | ELISA,IHC |
SSTR3 Proteins
SSTR3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP022726HU1 CSB-EP022726HU1 CSB-BP022726HU1 CSB-MP022726HU1 CSB-EP022726HU1-B |
Recombinant Human Somatostatin receptor type 3 (SSTR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF022726HU | Recombinant Human Somatostatin receptor type 3 (SSTR3) | in vitro E.coli expression system |
| CSB-MP022726HU | Recombinant Human Somatostatin receptor type 3 (SSTR3)-VLPs | Mammalian cell |
