TBRG1
TBRG1，全稱為轉(zhuǎn)化生長因子β調(diào)節(jié)蛋白1，無通用常用別名。它是一種胞內(nèi)調(diào)控蛋白，廣泛表達(dá)于人體各類組織，參與細(xì)胞生長、分化、凋亡調(diào)控，同時協(xié)同轉(zhuǎn)化生長因子β家族蛋白，維持組織穩(wěn)態(tài)、胚胎發(fā)育及免疫平衡，對機(jī)體正常生理功能運轉(zhuǎn)起到重要調(diào)節(jié)作用。 TBRG1表達(dá)異常與肺癌、乳腺癌、卵巢癌等惡性腫瘤密切相關(guān)，異常表達(dá)會打破細(xì)胞生長平衡，促進(jìn)腫瘤細(xì)胞增殖、侵襲轉(zhuǎn)移，同時參與腫瘤耐藥機(jī)制調(diào)控，提示患者預(yù)后不良。目前針對TBRG1的研究處于基礎(chǔ)階段，靶向抑制分子仍在臨床前探索，為實體腫瘤精準(zhǔn)治療提供潛在新方向。
熱銷產(chǎn)品
Recombinant Human Transforming growth factor beta regulator 1 (TBRG1) (CSB-EP023243HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TBRG1 Antibody (CSB-PA023243DSR1HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA023243DSR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA023243DSR1HU at dilution of 1:100
TBRG1 Antibodies
TBRG1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA023243GA01HU | TBRG1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA023243DSR1HU | TBRG1 Antibody | Human | ELISA, IHC |
TBRG1 Proteins
TBRG1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP023243HU CSB-MP023243HU CSB-EP023243HU-B |
Recombinant Human Transforming growth factor beta regulator 1 (TBRG1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023243HU | Recombinant Human Transforming growth factor beta regulator 1 (TBRG1) | E.coli |
| CSB-YP023243HU | Recombinant Human Transforming growth factor beta regulator 1 (TBRG1) | Yeast |
