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TERF1

Telomeric repeat-binding factor 1 is a protein in humans that is encoded by TERF1 gene. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

TERF1 Antibodies

TERF1 for Homo sapiens (Human)

TERF1 Proteins

TERF1 Proteins for Mus musculus (Mouse)

TERF1 Proteins for Homo sapiens (Human)

TERF1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)



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