TSPAN7
TSPAN7，全稱為四跨膜蛋白7，常用別名四跨膜超家族蛋白7。它是細胞膜上的四跨膜蛋白家族成員，廣泛表達于神經系統(tǒng)、免疫細胞及腫瘤組織，參與細胞黏附、信號傳遞、細胞增殖及免疫調節(jié)，對神經系統(tǒng)發(fā)育、免疫穩(wěn)態(tài)及腫瘤進展具有重要作用。 TSPAN7表達異常與神經系統(tǒng)疾病及腫瘤密切相關，表達不足會影響神經細胞發(fā)育及信號傳遞，與孤獨癥、智力低下等神經疾病相關；異常高表達則與肺癌、乳腺癌、白血病等腫瘤相關，促進腫瘤細胞增殖、侵襲及耐藥。目前TSPAN7靶向抑制劑處于臨床前研究階段，為神經疾病及腫瘤提供治療方向。
熱銷產品
Recombinant Human Tetraspanin-7 (TSPAN7) (CSB-CF025165HU(A4))
驗證數(shù)據(jù)
-SDS.jpg)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TSPAN7 Antibody (CSB-PA025165LA01HU)
驗證數(shù)據(jù)
Immunofluorescent analysis of HepG2 cells using CSB-PA025165LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA025165LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA025165LA01HU at dilution of 1:100
TSPAN7 Antibodies
TSPAN7 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025165LD01HU | TSPAN7 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA025165LB01HU | TSPAN7 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA025165LA01HU | TSPAN7 Antibody | Human | ELISA, IHC, IF |
| CSB-PA025165GA01HU | TSPAN7 Antibody | Human,Mouse | ELISA,WB |
TSPAN7 Proteins
TSPAN7 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP025165HU | Recombinant Human Tetraspanin-7 (TSPAN7), partial | E.coli |
| CSB-YP025165HU | Recombinant Human Tetraspanin-7 (TSPAN7), partial | Yeast |
| CSB-CF025165HU(A4) | Recombinant Human Tetraspanin-7 (TSPAN7) | in vitro E.coli expression system |
