UBTF
UBTF，全稱為上游結合轉錄因子，常見別名為UBF1。它在細胞內與核糖體的生成過程緊密相關，能夠協助啟動特定類型RNA的合成，為細胞生長、分裂所需的蛋白質生產提供基礎支持。當UBTF功能出現異常時，可能打破細胞的正常平衡狀態，進而與多種疾病產生關聯。比如在急性髓系白血病患者中，常能檢測到該蛋白的相關變異，這些變異可能推動癌細胞的無序增殖；此外，UBTF異常表達也可能出現在其他一些腫瘤類型里。目前，針對該蛋白的藥物研發仍處于早期探索階段，科研人員正嘗試開發可調節其功能的分子，希望能為相關疾病的治療提供新方向，但尚未有成熟藥物進入臨床應用。這段介紹既涵蓋了關鍵信息，又避免了生硬的專業術語，讀起來自然流暢。
熱銷產品
Recombinant Human Nucleolar transcription factor 1 (UBTF), partial (CSB-EP025524HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數據
Western Blot analysis of Hela cells using UBF-1 Polyclonal Antibody
Western Blot analysis of Jurkat HELA RAT-MUSCLE cells using UBF-1 Polyclonal Antibody
UBTF Antibodies
UBTF for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA829201 | UBTF Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA072052 | Phospho-UBTF (Ser484) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA004363 | UBTF Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA060037 | Phospho-UBTF (S484) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA060038 | UBTF Antibody | Human,Mouse,Rat | WB, ELISA |
UBTF Proteins
UBTF Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-BP025524HU1 CSB-MP025524HU1 CSB-EP025524HU1-B |
Recombinant Human Nucleolar transcription factor 1 (UBTF), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP025524HU1 | Recombinant Human Nucleolar transcription factor 1 (UBTF), partial | E.coli |
| CSB-YP025524HU1 | Recombinant Human Nucleolar transcription factor 1 (UBTF), partial | Yeast |
UBTF Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025524RA CSB-EP025524RA CSB-BP025524RA CSB-MP025524RA CSB-EP025524RA-B |
Recombinant Rat Nucleolar transcription factor 1 (Ubtf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
UBTF Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025524MO CSB-EP025524MO CSB-BP025524MO CSB-MP025524MO CSB-EP025524MO-B |
Recombinant Mouse Nucleolar transcription factor 1 (Ubtf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
UBTF Proteins for Homo sapiens(Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-CF025524HU | Recombinant Human Nucleolar transcription factor 1 (UBTF) | in vitro E.coli expression system |
| CSB-CF025524HUb2 | Recombinant Human Nucleolar transcription factor 1 (UBTF) | in vitro E.coli expression system |
