VCAN
VCAN，全稱為硫酸軟骨素蛋白聚糖，常用別名聚蛋白多糖。它是細胞外基質中的重要結構蛋白，廣泛分布于結締組織、軟骨、血管壁等組織，參與細胞外基質重塑、細胞黏附、炎癥反應調控，維持組織結構完整性與穩態，對軟骨發育、血管壁穩定具有重要作用。 VCAN異常表達與多種疾病密切相關，異常高表達會重塑腫瘤微環境，促進腫瘤細胞侵襲轉移，與肺癌、乳腺癌、膠質瘤等腫瘤相關；同時與關節炎、軟骨退變、纖維化疾病相關。目前VCAN阻斷劑處于臨床前研究階段，通過抑制其異常表達，為腫瘤及纖維化疾病提供治療方案。
熱銷產品
Recombinant Human Versican core protein (VCAN), partial (CSB-EP025810HU(A5))
驗證數據
-SDS.jpg)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數據
Western Blot analysis of mouse-brain cells using Versican Polyclonal Antibody
Human versican/PG-M/PG-350 ELISA kit (CSB-E11884h)
驗證數據
貨號：CSB-E11884h
規格：96T/48T
靈敏度：0.04 ng/ml.
檢測范圍：0.04 ng/ml-30 ng/ml.
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
VCAN Antibodies
VCAN for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007374 | VCAN Antibody | Human | WB, IHC, ELISA |
| CSB-PA248941 | VCAN Antibody | Human,Mouse,Rat | IHC,ELISA |
VCAN Proteins
VCAN Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025810HU CSB-EP025810HU CSB-BP025810HU CSB-MP025810HU CSB-EP025810HU-B |
Recombinant Human Versican core protein (VCAN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP025810HU(A5) | Recombinant Human Versican core protein (VCAN), partial | E.coli |
| CSB-BP025810HU(A5) | Recombinant Human Versican core protein (VCAN), partial | Baculovirus |
VCAN ELISA Kit
VCAN ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11884h | Human versican/PG-M/PG-350 ELISA kit | serum, plasma, tissue homogenates. | 0.04 ng/ml. |
